What is HLH Medical Abbreviation

What is HLH Medical Abbreviation - The medical abbreviation "HLH" stands for "Hemophagocytic Lymphohistiocytosis." HLH is a rare, life-threatening condition that affects the immune system, leading to uncontrolled activation of immune cells and excessive inflammation throughout the body. HLH can occur in two forms: primary (familial) HLH and secondary (acquired) HLH. Primary HLH is a genetic disorder that typically presents in infancy or early childhood, whereas secondary HLH can develop in individuals of any age, often triggered by an underlying condition or infection. In HLH, the immune system fails to regulate the activity of immune cells, such as natural killer (NK) cells and T cells, and macrophages. These cells become overactivated and release large amounts of cytokines, which are signaling molecules that mediate immune responses.

more...